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Toward a real time multi-tissue Adaptive Physics-Based Non-Rigid Registration framework for brain tumor resection

Our recent work to improve the accuracy of non-rigid registration while maintaining its completion within the neurosurgery time constrains published in Frontiers in Neuroinform., 17 February 2014. The new method can reduce the alignment error up to seven and five times compared to a rigid and ITK's physic-based non-rigid registration methods, respectively. On average, the alignment error of the new method is reduced by 9.23 and 5.63 mm compared to the alignment error from the rigid and PBNRR method implemented in ITK.